2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N8483
    Eprinomectin B1a
    		Inhibitor
    Eprinomectin B1a is a Eprinomectin (HY-12643) metabolite (an antiparasitic compound).
    Eprinomectin B1a
  • HY-Y1667R
    2,6-Dibromophenol (Standard)
    		Inhibitor
    2,6-Dibromophenol (2,6-DBP) is a weak inhibitor targeting voltage-gated Ca2+ channels. 2,6-Dibromophenol has no significant effect on potassium-induced calcium elevation in PC12 cells. 2,6-Dibromophenol shows a 48 h EC50 of 2.78 mg/L for Daphnia magna and a 96 h EC50 of 9.90 mg/L for algae (Scenedesmus quadricauda).
    2,6-Dibromophenol (Standard)
  • HY-111817A
    (Rac)-ACT-451840
    		Inhibitor
    (Rac)-ACT-451840 is an isomer of ACT-451840 that exhibits significant antimalarial effects. (Rac)-ACT-451840 exhibits significant antimalarial activity against P. berghei-infected mice at a dose of 20 mg/kg (ED90=13 mg/kg), and has an inhibitory effect at a dose of 300 mg/kg. The ED90 of (Rac)-ACT-451840 in the P. falciparum humanized immunodeficient mouse model is 3.7 mg/kg. (Rac)-ACT-451840 is similar to artemisinin, with a rapid onset of action but requires repeated high doses.
    (Rac)-ACT-451840
  • HY-N0402R
    Artemether (Standard)
    		Inhibitor
    Artemether (Standard) is the analytical standard of Artemether. This product is intended for research and analytical applications. Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria.
    Artemether (Standard)
  • HY-10373R
    Trimetrexate (Standard)
    		Inhibitor
    Trimetrexate (Standard) is the analytical standard of Trimetrexate (HY-10373). This product is intended for research and analytical applications. Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer.
    Trimetrexate (Standard)
  • HY-12651AR
    Primaquine (Standard)
    		Inhibitor
    Primaquine (Standard) is the analytical standard of Primaquine. This product is intended for research and analytical applications. Primaquine is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine prevents relapse in vivax and ovale malaria.
    Primaquine (Standard)
  • HY-B0688R
    Dapsone (Standard)
    		Inhibitor
    Dapsone (Standard) is the analytical standard of Dapsone. This product is intended for research and analytical applications. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al.
    Dapsone (Standard)
  • HY-118494R
    Ascaridole (Standard)
    		Inhibitor
    Ascaridole (Standard) is the analytical standard of Ascaridole. This product is intended for research and analytical applications. Ascaridole is an anthelmintic and also has antimalarial activity.
    Ascaridole (Standard)
  • HY-16762R
    Artefenomel (Standard)
    		Inhibitor
    Artefenomel (Standard) is the analytical standard of Artefenomel. This product is intended for research and analytical applications. Artefenomel (OZ439) is an orally active, synthetic anti-malarial compound containing an artemisinin pharmacophore with a mechanism of action similar to that of artemisinin. Artefenomel has antiviral activity against SARS-CoV-2.
    Artefenomel (Standard)
  • HY-13832S
    Atovaquone-d4
    		Inhibitor 99.8%
    Atovaquone-d4 is the deuterium labeled Atovaquone. Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
    Atovaquone-d<sub>4</sub>
  • HY-114197
    Antimalarial agent 14
    		Inhibitor 99.33%
    Antimalarial agent 14 (Compound N3) is a potent inhibitor of mitochondrial electron transport. Antimalarial agent 14 can serve as an anti-malarial agent.
    Antimalarial agent 14
  • HY-101476R
    Emodepside (Standard)
    		Inhibitor
    Emodepside (Standard) is the analytical standard of Emodepside. This product is intended for research and analytical applications. Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.
    Emodepside (Standard)
  • HY-126295
    MMV367
    		Inhibitor
    Anti-parasitic agent 3 is an anti-parasitic agent which active against agent resistant parasites.
    MMV367
  • HY-12642AR
    Diethylcarbamazine (Standard)
    		Inhibitor
    Diethylcarbamazine (Standard) is the analytical standard of Diethylcarbamazine (HY-12642A). This product is intended for research and analytical applications. Diethylcarbamazine is an orally active microfilaricidal agent used originally in onchocerciasis and lymphatic filiariasis. Diethylcarbamazine reduces eosinophil trafficking to the lung tissue and exerts anti-allergic effects. Diethylcarbamazine reduces serum levels of leptin, TNF-α, IL-6, MCP-1, glucose, insulin, and triglycerides, and ameliorates insulin resistance without altering body, liver, or adipose tissue weights. Diethylcarbamazine enhances reactive oxygen intermediate expression by polymorphonuclear neutrophils, increases lymphocyte proliferation, and inhibits actinomycetoma lesion development. Diethylcarbamazine can be used for the researches of bronchial asthma, insulin resistance and infection.
    Diethylcarbamazine (Standard)
  • HY-180558
    Acaricidal agent-2
    		Inhibitor
    Acaricidal agent-2 (compound 12aa) is a potent acaricidal agent that exhibits activity in T. cinnabarinus. Acaricidal agent-2 exhibits good ovicidal (LC50 = 0.14 mg/L) and larvicidal activities (LC50 = 0.09 mg/L). Acaricidal agent-2 shows low acute toxicity in Zebrafish. Acaricidal agent-2 can be used for pest management.
    Acaricidal agent-2
  • HY-B2138R
    Ethopabate (Standard)
    		Inhibitor
    Ethopabate (Standard) is the analytical standard of Ethopabate (HY-B2138). This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    Ethopabate (Standard)
  • HY-14461
    SJL 01
    		Inhibitor
    SJL 01 (Compound 8) is an anti-parasitic agent. SJL 01 (Compound 8) is cytotoxic to L-6 myocytes and exhibits antileishmaniasis activity both in vivo and in vitro. SJL 01 can be used for visceral leishmaniasis research.
    SJL 01
  • HY-136081
    Hexamidine
    		Inhibitor
    Hexamidine has amoebicidal effect that can be used for the research of Acanthamoeba keratitis.
    Hexamidine
  • HY-12404R
    Diminazene aceturate (Standard)
    		Inhibitor
    Diminazene (aceturate) (Standard) is the analytical standard of Diminazene (aceturate). This product is intended for research and analytical applications. Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.
    Diminazene aceturate (Standard)
  • HY-186053
    Antimalarial agent 56
    		Inhibitor
    Antimalarial agent 56 is an orally active antimalarial agent. Antimalarial agent 56 inhibits the growth of both drug-sensitive and drug-resistant Plasmodium falciparum strains in vitro. Antimalarial agent 56 can be used in malaria research.
    Antimalarial agent 56
Parasite Isoform Comparison

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